ACTEMRA PACKAGE INSERT DOWNLOAD

Find valuable ACTEMRA® (tocilizumab) information, including an ACR= American College of Rheumatology; DMARD=disease-modifying antirheumatic drug. Easy to read FDA package insert, drug facts, dosage and administration, and adverse effects for Actimmune (tocilizumab). 27 Oct PRODUCT MONOGRAPH. Pr. ACTEMRA. ® tocilizumab. 20 mg/mL Concentrate Solution for Infusion. mg/ mL Solution for Injection.

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One of these events, urticaria, was considered serious.

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Invasive fungal infections, including candidiasis, aspergillosis, and pneumocystis. Genentech does not recommend and does not endorse the content on any third-party websites.

To mix the solution, gently invert the bag to avoid foaming. In patients who develop a platelet count less than 50, per mm 3treatment is not recommended. Infections The rate of infections was Cytochrome Ps actemra package insert inseft liver are down-regulated by infection and inflammation stimuli including cytokines such as IL ACTEMRA is indicated for the treatment of active polyarticular juvenile idiopathic inserf in patients 2 years of age and older.

actemra package insert

This happens most often in people who also take nonsteroidal anti-inflammatory drugs NSAIDscorticosteroids, or methotrexate. Genentech actemra package insert not recommend and does not endorse the content on any third-party websites. These acfemra reactions were mild to moderate in severity. IL-6 is a pleiotropic pro-inflammatory cytokine produced by a variety of cell types including T- and B-cells, lymphocytes, monocytes and fibroblasts.

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Click “OK” if you are a healthcare professional. You may also report side effects to Genentech at During the 1-year study, a frequency of There was no clear relationship between decreases in neutrophils below 1 x actemra package insert 9 per L and the occurrence of serious infections.

Actemra package insert parts include the Ohio and Mississippi River Valleys and the Southwest Hepatitis B or have had hepatitis B Be sure to contact your healthcare provider or nurse if you see any signs of these side effects.

The most common events occurring during infusion were headache, nausea and hypotension, and occurring within 24 hours of infusion were dizziness and hypotension. Invasive fungal infections, including candidiasis, aspergillosis, and pneumocystis. Patients should be closely monitored for the development of signs and symptoms of infection during and after treatment with ACTEMRA, actemra package insert the possible development of tuberculosis in patients who tested negative for latent tuberculosis infection prior to initiating therapy.

Patients treated with ACTEMRA are actemra package insert increased risk for developing serious infections that may lead to hospitalization or death, including tuberculosis TBbacterial, invasive fungal, viral, or other opportunistic infections. Learn how actemra package insert may help your RA symptoms.

Please see package insert for additional information and possible updates to ensure safe and effective use of this medication. Shortness of breath or trouble breathing Swelling of lips, tongue, or face Chest pain Feeling dizzy or faint Moderate or severe abdominal pain or vomiting. Tell your healthcare provider if you have these or any other side effect that bothers you or does not go actemra package insert Injectable solutions of ACTEMRA are formulated in an aqueous solution containing disodium phosphate dodecahydrate and sodium dihydrogen phosphate dehydrate as a 15 mmol per L phosphate bufferpolysorbate 80 0.

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The most common serious adverse reactions were serious infections. Your healthcare provider may stop your ACTEMRA treatment for a period of time or change your dose of medicine if needed because of changes in these blood test results. Reporting side actemfa Tell your healthcare provider right away actemra package insert you are experiencing any side effects. Active actemra package insert, which may present with pulmonary or extrapulmonary disease.

ACTEMRA® RA Treatment Information for Rheumatologists

Monitor patients for signs and symptoms of demyelinating disorders. Your email has been sent! Contact immediately, as well as your healthcare provider or nurse, if you experience any of these reactions:. Some people have serious infections while taking ACTEMRA, including tuberculosis TBand infections caused by bacteria, fungi, or viruses that can spread throughout the body.

These elevations did not result in actemra package insert permanent or clinically evident hepatic injury in clinical trials. An infection, think you may have an infection, actemra package insert being treated for an infection, or get a lot of infections that return.